What cut of meat should I use?

The best cut is u003cstrongu003echuck roastu003c/strongu003e—it’s well-marbled and becomes super tender when slow-cooked. You can also use bottom round roast or brisket, but chuck roast gives the best flavor and texture.

Can I make it without pepperoncini peppers?

Yes, you can leave them out, but the peppers add a subtle tang and depth of flavor. If you skip them, consider adding a splash of vinegar or a squeeze of lemon juice for balance.

Can I make it in the oven or Instant Pot?

Absolutely! The u003cstrongu003eovenu003c/strongu003e method takes 3–4 hours at 275°F in a covered Dutch oven. The u003cstrongu003eInstant Potu003c/strongu003e method takes 60–70 minutes on high pressure with a natural pressure release.

Can I use a homemade ranch or au jus mix?

Yes! For u003cstrongu003ehomemade ranchu003c/strongu003e, mix: 1 tsp dried dill, 1 tsp dried parsley, 1 tsp garlic powder, 1 tsp onion powder, 1 tsp dried chives, ½ tsp salt, and ½ tsp pepper. For u003cstrongu003ehomemade au jusu003c/strongu003e, use: 1 tbsp beef bouillon, 1 tsp onion powder, ½ tsp garlic powder, ½ tsp black pepper, and a pinch of cornstarch.

Mississippi Pot Roast Recipe – Easy,Juicy with 5 ingredients

Ingredients

Scale

3 –4 lb chuck roast
1 packet ranch dressing mix
1 packet au jus gravy mix
½ cup unsalted butter
6 –8 pepperoncini peppers
Optional: ¼ cup pepperoncini juice

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Instructions

Place roast in cooker. Sprinkle with ranch + au jus.
Top with butter and peppers.
Cook low for 8 hours.
Shred, mix into juices, and serve warm.

Notes

Nutrition (Approx. per Serving):

Calories: 450
Fat: 33g
Carbs: 2g
Protein: 35g
Sodium: 900mg

Prep Time: 10 minutes
Cook Time: 8 hours
Category: Main Course
Cuisine: American, Southern-Inspired